Effect of kidney-supplementing and blood-activating method on expression of Malb and RBP in senile patients with isolated systolic hypertension
10.3760/cma.j.issn.1673-4246.2013.04.009
- VernacularTitle:补肾活血法对老年单纯收缩期高血压患者微量白蛋白、视黄醇结合蛋白水平的影响
- Author:
Yelin SONG
;
Weijun XU
;
Guangyu YU
;
Lingbo WEI
;
Weifeng CHI
;
Yingying NIE
- Publication Type:Journal Article
- Keywords:
Kidney-supplementing and blood-activating method;
Isolated systolic hypertension;
Malb;
RBP
- From:
International Journal of Traditional Chinese Medicine
2013;35(4):313-315
- CountryChina
- Language:Chinese
-
Abstract:
Objective Kidney-supplementing and blood-activating method was adopted in treating senile patients with isolated systolic hypertension to observe its decompression effects and influences on microalbunminuria (Malb),retinol binding protein (RBP) level in 24 hours.Methods 90 patients with simple systolic hypertension were randomly recurited into two groups.52 cases in the treatment group were administered with kidney-supplementing and blood-activating decoction,including 1 case falling off and 51 cases entering statistical analysis; 38 cases in the control group were administered with oral placebo,among them 2 cases were fallen offand 36 cases were entered statistical analysis.Both groups were treated for 8 weeks.Results () Blood pressure:systolic blood pressure at 4 and 8 weeks after the treatment in the treatment group [(144.03±12.33)mmHg (1 mmHg=0.133kPa) and (132.27±13.15)mmHg] wassignificantlyimproved than before the treatment [(156.32±12.05)mm Hg] (P＜0.05),and also significantly better than the control group at 4,8 weeks after the treatment [(151.19± 13.83)mm Hg,(152.74± 12.03)mm Hg] (P＜0.05).②The Malb,RBP level:Malb,RBP level [(40.80±13.51)mg/L,(150.43±23.62)mg/L] after the treatment in the treatment group was reduced than before the treatment [(50.14± 15.61)mg/L,(220.04±30.20) mg/L] (P＜0.05),and was significantly different to the control group after treatment [(52.12±14.69)mg/L,(219.34±34.37)mg/L] (P＜0.05).Conclusion Kidney-supplementing and blood-activating method can improve kidney function,and thus to reduce the effect of systolic blood pressure.
