Research progress in microRNA regulation of tumor glucose metabolism
10.3760/cma.j.issn.1673-4203.2013.07.018
- VernacularTitle:MicroRNA与肿瘤糖代谢研究进展
- Author:
Jun HU
;
Baobing YIN
- Publication Type:Journal Article
- Keywords:
Glucose Metabolism;
Glycolysis;
MicroRNAs;
Neoplasms
- From:
International Journal of Surgery
2013;40(7):489-492
- CountryChina
- Language:Chinese
-
Abstract:
Aerobic glycolysis,which is also termed as Warburg effect,is one of the most common and profound biochemical phenotypes of tumor ceils.Several oncogenes and tumor suppressors genes have been implicated in aerobic glycolysis.MicroRNAs can control this metabolic switch by regulating oncogenes and tumor suppressors genes in a post-transcriptional way.A deeper understanding of the mechanisms and pathways by which miRNAs regulate the aerobic glycolysis will hopefully lead to a new therapeutic strategy for malignant cancer.
