Literary analysis of the adverse reactions of Niuhuang-Jiedu pill

VernacularTitle:牛黄解毒片不良反应文献分析
Author: Jianteng NI ; Kuijun ZHAO
Publication Type:Journal Article
Keywords: Niuhuang-Jiedu pill; ADR; Proprietary Chinese medicines
From: International Journal of Traditional Chinese Medicine 2013;35(4):295-297
CountryChina
Language:Chinese
Abstract: Objective To Summariz and discuss the adverse reactions of Niuhuang-Jiedu pill (NJP) in the treatment.Methods Retrieved ADR report literatures through Chinese Medical Journal Database (CMJD) and WANFANG DATA from 1970 to 2012 with NJP as the key words,got and analyzed datas including patient age,gender,dosage,medication time and ADR type.Results Sixty-eight literatures with seventy-seven ADR report cases were retrieved.Adverse action induced by NJP was mainly allergic response,including arseniasis,gastrointestinal,uropoiesis reactions.Among 77 ADR cases,47 cases were considered as allergic response,61.0％ of the total,one death and thirteen shock cases were included.The number of arseniasis,gastrointestinal,uropoiesis reactions cases were respectively 14.3％,11.7％,6.5％ of the total.Conclusion The ADR of NJP should not be ignored.Allergy history,dosage and medication time should be pay more attention to to prevent the ADR of NJP to the fullest extemt.