Progress of versican in the occurrence and development of neoplasms
10.3760/cma.j.issn.1673-4203.2013.07.017
- VernacularTitle:多功能蛋白聚糖与肿瘤发生发展关系的研究进展
- Author:
Helin FENG
;
Yaheng ZHAO
;
Lihua ZHENG
;
Jiangang FENG
- Publication Type:Journal Article
- Keywords:
Versican;
Neoplasms;
Breast neoplasms;
Liver neoplasms;
Chondrosarcoma
- From:
International Journal of Surgery
2013;40(7):485-488
- CountryChina
- Language:Chinese
-
Abstract:
Versican comes from fibroblasts and belongs to chondroitin sulfate proteoglycan.It distributes in various tissues.The versican have functions including regulate cell growth and differentiation,promote cell proliferation,invasion and metastasis,and stimulate angiogenesis.Experiments have confirmed that the expression of versican is involved in various cancers.Here,the author do an overview of versican in the occurrence and development of breast cancer,liver cancer and chondrosarcoma aimed to further explore the pathogenesis of tumors.
