Research status of collateral circulation of chronic cerebral hypoperfusion in rats
10.3760/cma.j.issn.1673-4165.2013.06.013
- VernacularTitle:慢性脑低灌注大鼠的侧支循环研究现状
- Author:
Zhen JING
;
Shijun ZHANG
;
Lian HUANG
- Publication Type:Journal Article
- Keywords:
Brain Ischemia;
Collateral Circulation;
Cognition Disorders;
Disease Models,Animal;
Rats
- From:
International Journal of Cerebrovascular Diseases
2013;21(6):477-480
- CountryChina
- Language:Chinese
-
Abstract:
Collateral circulation may be a potential therapeutic target for ischemic stroke.However,aiming at improving the treatment of collateral circulation,it has not yet got the reliable clinical validation now.Therefore,undergoing the study of collateral circulation first in the animal models of chronic cerebral hypoperfusion has important practical significance.This article reviews the methods of rat chronic cerebral hypoperfusion models,neurobehavioral evaluation,cerebral perfusion assessment,collateral circulation pathways,and the experimental research status of improving collateral circulation.
