Mild hypothermia for ischemic stroke: translation from experiments to clinical practice
10.3760/cma.j.issn.1673-4165.2013.06.011
- VernacularTitle:亚低温治疗缺血性卒中:从实验向临床转化
- Author:
Xueying WANG
;
Dan YU
- Publication Type:Journal Article
- Keywords:
Hypothermia,Induced;
Stroke;
Brain Ischemia
- From:
International Journal of Cerebrovascular Diseases
2013;21(6):469-472
- CountryChina
- Language:Chinese
-
Abstract:
As a neuroprotective measure,the application and research of mild hypothermia in clinical practice have been very extensive.Using mild hypothermia has achieved a positive efficacy in many diseases,such as brain damage after cardiac arrest and neonatal hypoxic-ischemic encephalopathy,etc.Although mild hypothermia has a large number of animal experiments and clinical studies in the treatment of ischemic stroke,and animal experiments have confirmed that it has the exact neuroprotective effect,the neuroprotective effect of mild hypothermia in the treatment of ischemic stroke has not yet come to a unified conclusion in the clinical studies.Its clinical efficacy does not seem to be as optimistic as expected.Therefore,it is necessary to analyze the transforming problems of mild hypothermia for treatment of ischemic stroke from animal experiments to clinical practice,and to provide ideas for the clinical application of mild hypothermia for treatment of ischemic stroke.
