A prospective study of event-related potentials in patients with first-episode mild-and-moderate depressions treated with Qishen Fukang Capsules

VernacularTitle:芪参复康胶囊治疗首发轻中度抑郁症患者事件相关电位的变化
Author: Jiu CHEN ; Laiqi YANG ; Xintian LI ; Yu LIN ; Fan XU ; Qinghai FU ; Yan ZHANG
Publication Type:Journal Article
Keywords: Qishen Fukang capsules; Event-related potentials
From: Chinese Journal of General Practitioners 2013;12(4):296-298
CountryChina
Language:Chinese
Abstract: A total of 72 patients with first-episode mild-and-moderate depression took Qishen Fukang Capsules.The change of event-related potential P3 was determined before and after treatment for 6,12 and 24 weeks.And another 70 healthy controls received the same tests simultaneously.Compared with before treatment,HAMD scores after treatment were lower in the patient group [(29.1 ± 5.1) score vs.(10.4 ±4.1) score].P3 latencies were shorter and amplitudes became higher after treatment (P ＜0.01).And the difference of before and after treatment for 6 weeks was larger than the difference of 12 weeks and after treatment for 6 weeks (P ＜ 0.01).The curative effect is definite.And the clinical symptoms and brain evoked potential index have improved in patients with first-episode mild-and-moderate depression after medication.