Effect of curcumin on expression of resistin mRNA in rats with insulin resistance
10.3760/cma.j.issn.1000-6699.2013.07.020
- VernacularTitle:姜黄素对胰岛素抵抗大鼠抵抗素表达的影响
- Author:
Shuting BAI
;
Xiaojuan ZHAO
;
Fan WANG
;
Wei CHEN
;
Nannan WANG
- Publication Type:Journal Article
- Keywords:
Insulin resistance;
Hyperinsulinaemic-euglycaemic clamp;
Curcumin;
Resistin
- From:
Chinese Journal of Endocrinology and Metabolism
2013;29(7):618-620
- CountryChina
- Language:Chinese
-
Abstract:
By feeding rats with high-fat diet insulin resistant models were induced.Some of the models were treated with intragastric administration of curcumin,then the effects were evaluated by hyperinsulinaemic-euglycaemic clamp technique.Curcumin reduced the level of serum resistin and the expression of resistin mRNA in adipose tissue,and thus ameliorated insulin resistance in rats.