Correlation between inflammatory factors and subclinical atherosclerosis in type 2 diabetic patients with metabolic syndrome
10.3760/cma.j.issn.1000-6699.2013.07.014
- VernacularTitle:炎症因子与2型糖尿病合并代谢综合征患者亚临床动脉粥样硬化的关系
- Author:
Yingfen QIN
;
Didi HUANG
;
Jia ZHOU
;
Jiale QIAN
;
Chan JIANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Metabolic syndrome;
Subclinical atherosclerosis;
Mannose-binding lectin;
High sensitive-C reactive protein;
Plasminogen activator inhibitor 1
- From:
Chinese Journal of Endocrinology and Metabolism
2013;29(7):592-594
- CountryChina
- Language:Chinese
-
Abstract:
ELISA technique was employed to determne the concentration of mannose binding lectin (MBL),plasminogen activator inhibitor-1 (PAI 1),and high sensitive ()eactive protein (hs-CRP).hs CRP level m patients with subclinical atherosclerosis was significantly higher (P ＜ 0.01),MBL level was of no significant difference (P＞0.05) ; PAI-1 was significantly higher (P＜0.01) only m those with metabolic syndrome(MS).Taking no account of subclinical atherosclerosis,MBL of diabetic patients with MS was significantly lower while hs-CRP and PNI 1 were signific amlv higher (P ＜ 0.01).Inflammatory faetors MBL,hs-CRP,and PAI-1 involved in the -ube linical atherosclerosis development in the type 2 diabetic patients with MS.
