Research advances in the association between gut microbiota imbalance and colorectal cancer
10.3760/cma.j.issn.1674-635X.2013.04.007
- VernacularTitle:肠道微生态失衡与大肠癌发生相关性研究进展
- Author:
Renyuan GAO
;
Huanlong QIN
- Publication Type:Journal Article
- Keywords:
Colorectal cancer;
Microbiota;
Imbalance
- From:
Chinese Journal of Clinical Nutrition
2013;21(4):229-234
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer (CRC) is a malignant digestive tract tumor resulted from genetic and environmental factors and can be accompanied by a series of gene mutations.The etiology of CRC,particularly the role of gut microbiota imbalance,has became a hot research topic along with the increase of its prevalance.In this article,we elucidate the potential roles and mechanisms of streptococcus gallolyticus,fusobacterium,Escherichia coli,Bacteroides fragilis,and helicobacter wlori in the development of CRC,with an attempt to further understand the functions of microbiota,search for possible specific carcinogenic strains,and improve the management of CRC.
