Safety of kidney donors after living-related kidney transplantation
10.3969/j.issn.2095-4344.2013.44.004
- VernacularTitle:亲属活体肾移植后供者安全性评价
- Author:
Hanlan LU
;
Yu CHEN
;
Shangxi FU
;
Meisheng ZHOU
;
Youhua ZHU
;
Xueyang ZHENG
- Publication Type:Journal Article
- Keywords:
kidney transplantation;
living donors;
proteinuria;
hypertension
- From:
Chinese Journal of Tissue Engineering Research
2013;(44):7681-7686
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Fol ow-up researches have shown that there is no statistical y difference in safety between kidney donor and healthy person after kidney transplantation, even the donors wil have better life quality. OBJECTIVE:To evaluate the safety of living-related kidney transplantation in living kidney donors. METHODS:Ninety-four cases of kidney donors received 1-10 years fol ow-up through regular clinical fol ow-up, telephone fol ow-up and regular renal patients self-help groups to compare the changes of serum creatinine, hematuria, proteinuria and blood pressure and lipid level in the donors before and after kidney transplantation. RESULTS AND CONCLUSION:The serum creatinine was significantly increased after nephrectomy (P<0.01), but al the donors had normal serum creatinine levels and remained stable. There was no significant difference in serum creatinine level between the latest fol ow-up and discharge (P>0.05). After nephrectomy, three cases (3.2%) suffered from hematuria, two cases (2.1%) had proteinuria, and improved after rest;six cases (6.4%) were subject to hypertension and six cases (6.4%) to hyperlipidemia. Al of the donors were alive. The living donor nephrectomy is feasible and safe. Preoperative assessment and long-term postoperative fol ow-up can guarantee the safety of the donors.
