Research progress of neuropathology of autism
10.3760/cma.j.issn.1673-4408.2013.04.016
- VernacularTitle:儿童孤独症神经病理学研究进展
- Author:
Di WANG
- Publication Type:Journal Article
- Keywords:
Autism;
Children;
Neuropathology
- From:
International Journal of Pediatrics
2013;40(4):385-387
- CountryChina
- Language:Chinese
-
Abstract:
Childhood autism is an extensive developmental disorder.Abnormal neuroimaging and neuropathology brain structure research of autistic children in recent years are reviewed in this paper.Brain structure researches have showed the brain volume increased in children with autism,normally occuring to the frontal lobe,temporal lobe.Brain function researches have shown that children with autism have abnormal activity in the fusiform gyrus,superior temporal gyrus,and inferior frontal lobe.Brain metabolites studies have shown that children with autism present glutamate and gamma-aminobutyric acid and serotonin metabolism disorder.Immunological studies have found that children with autism have proinflammatory factor and the emergence of a brain protein antibody.
