Clinical analysis of 32 metastatic gastric cancer patients who un-derwent surgery after chemotherapy

VernacularTitle:32例化疗后接受手术治疗的晚期胃癌患者的临床分析
Author: Yongkun SUN ; Lin YANG ; Yihebali CHI ; Jing HUANG ; Aiping ZHOU ; Xinghua YUAN ; Jianqiang CAI ; Jinwan WANG
Publication Type:Journal Article
Keywords: metastatic gastric cancer; chemotherapy; surgery; overall survival
From: Chinese Journal of Clinical Oncology 2013;(16):988-991
CountryChina
Language:Chinese
Abstract: Objective:To examine metastatic gastric cancer patients who underwent surgery after chemotherapy and to determine the factors affecting survival. Methods:Clinical data on metastatic gastric cancer patients who underwent surgery after chemotherapy were retrospectively analyzed. The overall survival data were evaluated through the Kaplan-Meier method, Log-rank test, and Cox haz-ards regression. Results:The median age was 46 (22~74), and the median overall survival rate (OS) was 19 months (4~59 months). Response to chemotherapy (23.0 m for PR and 14.5 m for SD, P=0.045) and resection of the primary tumor (23.0 and 5.5 m, respective-ly, P=0.017) affected OS. No single factor was related to OS according to Cox regression. Conclusion:Surgical removal of the primary tumor is recommended for metastatic gastric cancer patients with positive response to chemotherapy and with a primary tumor that can be resected.