Preliminary study on pelvic organ prolapse treated by using small intestinal submucosa mesh
10.3760/cma.j.issn.0529-567x.2013.08.004
- VernacularTitle:猪小肠黏膜下层生物补片在盆腔器官脱垂手术治疗中应用的初步观察
- Author:
Xiuli SUN
;
Xin YANG
;
Jing GENG
;
Jianliu WANG
- Publication Type:Journal Article
- Keywords:
Pelvic organ prolapse;
Intestine,small;
Intestinal mucosa;
Transplants;
Gynecologic surgical procedures;
Treatment outcome
- From:
Chinese Journal of Obstetrics and Gynecology
2013;48(8):575-578
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study clinical efficacy of porcine-derived small intestinal submucosa (Surgisis) in treatment of pelvic organ prolapse (POP).Methods From Mar.2012 to Mar.2013,15 patients with POP at more than Ⅲ of POP quantitation (POP-Q) staging system undergoing pelvic reconstructive surgery with Surgisis in Peking University People's Hospital.The mean age was 59 years old (39-82).The variable site of POP-Q staging systemn was compared between preoperative and postoperative status among those patients.Quality of life questionnaire of pelvic floor impact questionnaire (PFIQ-7),pelvic floor distress inventory short form (PFDI-20) and PISQ-31 were studied to evaluate subjective satisfaction,recurrence and the quality of life's improvement.Results All patients were followed up at mean of 9.9 months (3-15 months),the mean time of surgery was 96 mins (65-120 mins),the mean blood loss was 159 ml (50-500 ml).No infection and erosion was observed on those patients.The rate of subjective satisfaction was 14/15,the recurrence rate of prolapse was 2/15.Scoring system of PFDI-20 was from 87 (56-124) at operative status to 30 (22-48) at postoperative status.PFIQ-20 was from 129 (85-158) at preoperative status to 24 (18-48) at postoperative status.PISQ-31 was from 48 (32-55) at preoperative status to 79 (66-89) at postoperative status,which all reached statistical difference (all P ＜0.05).Total 9 patients obtained satisfactory sexual life.Conclusions The short-term clinical effect of pelvic reconstructive surgery with Surgisis was satisfied,quality of life and sexual life was improved,and less complication were observed.However,long-term clinical effect on patients should be warranted to follow up.
