Microsurgery for parasellar menningiomas and impact factors of recurrence
10.3969/j.issn.1672-7347.2013.07.009
- VernacularTitle:鞍旁脑膜瘤显微手术疗效及远期复发分析
- Author:
Dun YUAN
;
Dingyang LIU
;
Xianrui YUAN
;
Weixi JIANG
;
Duanwu LUO
;
Qing LIU
;
Zefeng PENG
;
Xiping DING
;
Zhiquan YANG
- Publication Type:Journal Article
- Keywords:
parasellar meningioma;
microsurgery;
tumor recurrence
- From:
Journal of Central South University(Medical Sciences)
2013;38(7):699-703
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of microsurgery for parasellar menningiomas and to analyze the impact factors of recurrence. Methods:Clinical and follow-up data in a consecutive series of 134 patients with parasellar meningiomas were retrospectively analyzed. Results:A total of 109 patients (81.3%) had radical removal (Simpson grade I and II), and 116 patients were followed up for an average period of 81.6 months. The mean quality of life score (KPS) was 91.9, 90 patients regained full daily activity and 16 patients were able to take care of themselves. Oculomotor paralysis occurred in 7 patients, epilepsy in 8, and another 9 patients suffered hemispheral paralysis. Tumor recurred atfer the radical removal in 12 out of the 96 follow-up patients (12.5%). Tumor progressed atfer subtotal removal in 12 out of the 20 follow-up patients (60%). Tumor with cavernous sinus (CS) invasion had significantly higher risk of recurrence campared with non-CS invasion (P=0.043). The recurrence rate increased with the pathological grade (P<0.01). Conclusion:Patients with parasellar meningiomas undergoing microsurgical resection may have a good long-term function outcome. For most patients, total removal by microsurgery is the ifrst choice. Careful follow-up is needed if tumor invaded the CS and radiosurgery is proposed for WHO grade 1 and 2.
