Tumor necrosis factor-related apoptosis inducing ligand and its receptors in hepatocellular carcinoma
10.3760/cma.j.issn.1673-422X.2013.08.015
- VernacularTitle:肿瘤坏死因子相关凋亡诱导配体及其受体与肝癌
- Author:
Jian XU
;
Jingdong LI
- Publication Type:Journal Article
- Keywords:
TNF-related apoptosis-inducing ligand;
Receptors,TNF-related apoptosis-inducing ligand;
Liver neoplasms
- From:
Journal of International Oncology
2013;40(8):605-607
- CountryChina
- Language:Chinese
-
Abstract:
Tumor necrosis factor-related apoptosis inducing ligands (TRAILs) and their receptors can specifically express in hepatocellular carcinoma cells.TRAIL can specifically induce tumor cells apoptosis through death receptors (DRs) ; TRAIL combined radiation and chemotherapy can effectively overcome the TRAIL resistance of tumor cells,and promote the apoptosis of tumor cells,meanwhile the gene therapy of TRAIL on anti-tumor clinical treatment has been widely used.
