Regulation role of resveratrol in microRNAs expression in cancers
10.3760/cma.j.issn.1673-422X.2013.08.009
- VernacularTitle:白藜芦醇对肿瘤中微小RNA的调节作用
- Author:
Jiawen JI
;
Huaijun ZHOU
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplasms;
Resveratrol
- From:
Journal of International Oncology
2013;40(8):587-590
- CountryChina
- Language:Chinese
-
Abstract:
As a kind of polyphenolic phytoalexin,resveratrol exerts protective roles in anti-tumor,antiinflammatory and promoting metabolism.Resveratrol's anti-tumor mechanisms may be involved in upregulating tumor suppressor microRNAs and downregulating oncogenic microRNAs,and affect its relative pathways and target genes in different cancers such as colon cancers and breast cancers.This will provide a new theoretical basis for the further clarification of resveratrol-associated tumor suppressing mechanisms and its application to the clinical.
