Human papillomavirus infection and genotype distribution in cervical adenocarcinoma: problems should be noticed

VernacularTitle:子宫颈腺癌人乳头状瘤病毒感染与型别分布研究中应注意的问题
Author: Shaokai ZHANG
Publication Type:Journal Article
Keywords: Uterine cervical neoplasms; Adenocarcinoma; Human papillomavirus; Genotype
From: Cancer Research and Clinic 2013;25(7):502-504
CountryChina
Language:Chinese
Abstract: Cervical cancer is one of the most common cancer in women worldwide.The incidence of squamous cell carcinoma (SCC) has decreased significantly in countries with cervical cancer screening programs over the past decades.However,an increasing of both absolute and relative incidence of cervical adenocarcinoma (CADC) has been observed worldwide,including countries where screening is routinely implemented,indicating that conventional screening programs can' t offer adequate protection against CADC.Since human papillomavirus (HPV) is an important etiologic factor of CADC,CADC may be effectively prevented by prophylactic vaccine and screening based on HPV DNA test.But it needs reliable data of HPV infection and genotype distribution in CADC to assess the potential benefits of vaccination and screening based on HPV DNA test.This review summarizes the problems in researches regarding to HPV infection and genotype distribution in CADC and finds out the solutions.