Study on endoscopic nasopancreatic drainage in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis
10.3760/cma.j.issn.0254-1432.2013.04.009
- VernacularTitle:鼻胰管引流在预防内镜逆行胰胆管造影术后胰腺炎中的研究
- Author:
Xujian CHEN
;
Yiyu SHEN
;
Zhengxiang ZHONG
- Publication Type:Journal Article
- Keywords:
Cholangiopancreatography,endoscopic retrograde;
Pancreatitis;
Drainage
- From:
Chinese Journal of Digestion
2013;33(4):248-252
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of endoscopic nasopancreatic drainage (NPD) in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) in a high-risk population.Methods From April 2009 to February 2012,a total of 105 cases of PEP high risk population were collected and divided into non NPD group (n=58) and NPD group (n=47) according to the situation during the endoscopic retrograde cholangiopancreatography(ERCP) operation.NPD was placed in NPD group,the head of the drainage passed the neck of pancreas under X-ray.Nasobiliary drainage or no drainage was assigned to the group of non NPD group according to the situation during operation.x2 test and t-test were performed for comparing and analyzing the clinical data before and post operation,the incidence and risk ratio of PEP between the two groups.Results Twenty-four hours after ERCP,the mean level of serum amylase at 24 h (t=2.419),the degree of abdominal pain (t3h=2.585,t24h=7.236) and relief time (t=4.996) of NPD group were better than those of non NPD group (all P＜0.05).The incidence of PEP in NPD group was 6.7％(3/45) and non NPD group was 29.3 ％ (17/58),the incidence of PEP in the NPD group was significantly lower than that in the non NPD group (x2 =8.304,P＜0.01),and the relative risk was 0.172 (95％CI:0.047 to 0.632,P＜0.01).Conclusion The regular placement of endoscopic NPD is a practical,effective and easy way to prevent PEP in high risk population.
