Prognosis factor analysis for rectal neuroendocrine tumor
10.3760/cma.j.issn.1007-5232.2013.07.001
- VernacularTitle:影响直肠神经内分泌肿瘤预后的相关因素分析
- Author:
Man MENG
;
Enqiang LINGHU
;
Po ZHAO
;
Zhongsheng LU
;
Zhiqiang WANG
;
Yonghua WANG
;
Qiyang HUANG
- Publication Type:Journal Article
- Keywords:
Intestinal tumor;
Rectum;
Carcinoid tumor;
Pathological;
Prognosis
- From:
Chinese Journal of Digestive Endoscopy
2013;30(7):361-364
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the related prognostic factors influencing rectal neuroendocrine tumor prognosis.Methods We retrospectively reviewed tumor clinical and pathology material of 183 cases with rectal neuroendocrine in our hospital during recent 10 years and reclassified them according to the 2010 WHO pathology classification.Single factor and multivariate analysis were performed to find related prognostic factors.Results Single factor analysis showed that tumor size (＜ 1 cm,1-2 cm,＞2 cm,98.77％ vs 78.57％ vs 28.57％,x2 =71.4793,P =0.0001),pathological grading (G1,G2,G3,98.73％ vs.76.19％ vs 25.00％,x2 =56.5121,P =0.0001) and the stage (stage Ⅰ,Ⅱ,Ⅲ,Ⅳ period,99.40％ vs 50.00％ vs 60.00％ vs 16.67％,x2 =105.0383,P =0.0001) among the three variables survival difference was statistically significant.Multivariate analysis (Cox regression) indicated that the tumor stage were independent factors affecting the prognosis,regression coefficient was 1.277 (B),Wald value of 28.145,Exp (B) a value of 3.586,95％ CI:2.237-5.747.Conclusion Tumor staging is an independent risk factor of survival,without considering other factors,different tumor size and pathologic grade also have different prognosis.Clinicians in making treatment plan should fully consider the above factors before choosing the appropriate follow-up plan.
