Clinicopathological features of polypoid lesions of the gallbladder: report of 1396 cases

VernacularTitle:胆囊息肉样病变1396例临床病理学特征分析
Author: Dapeng ZHANG ; Naiqiang CUI
Publication Type:Journal Article
Keywords: Gallbladder disease; Polyps; Adenocarcinoma; Adenomatous polyposis
From: Chinese Journal of General Surgery 2013;28(8):604-606
CountryChina
Language:Chinese
Abstract: Objective To probe the differences in clinicopathological features between benign and malignant polypoid lesions of the gallbladder.Methods In this study,1396 PLG cases diagnosed by postoperative pathology between 2007.1 to 2009.12 were enrolled.Cases were divided into three groups according to the pathological classification:1339 cases of benign proliferative diseases ;42 cases of adenoma,15 cases of malignant disease.Comparing the clinical characteristics of the three groups,we screened out the risk factors for malignant transitions.Results Age (F =8.090,P =0.000),size of polyp (F =102.61,P =0.000),single vs multiple lesions (x2 =214.25,P =0.000),concurrent inflammation (x2 =9.362,P =0.009),and stones (x2 =34.022,P =0.000) were significantly different between the three groups.Conclusions Size of polyps over 0.8 cm,age over 60 years,single polyp,accompanied by stones and inflammation were the risk factors for malignancy in gallbladder polypoid lesions.