Prognosis of breast conservation therapy in young woman breast carcinoma
10.3760/cma.j.issn.1007-631X.2013.08.009
- VernacularTitle:年轻乳腺癌保乳手术治疗的预后分析
- Author:
Lina ZHANG
;
Yanfang YANG
;
Jun LIU
;
Zhansheng JIANG
;
Lin GU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Masectomy,segmental;
Age factors;
Prognosis
- From:
Chinese Journal of General Surgery
2013;28(8):593-596
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the clinical characteristics and prognostic factors in young women of breast cancer treated with breast conservation therapy.Methods Clinical data of 605 cases of breast cancer patients undergoing breast conserving therapy were reviewed in our hospital from Jan 1998 to July 2008.According to their age,these patients were divided into young group (age≤ 35 years,n =110 cases) and the elderly group (age ＞ 35 years,n =495 cases).Survival factors were analyzed by Cox proportional hazards regression model.Results During the median follow-up of 61 months,the 5-year local-regional relapse-free survival was 92.6％ and 96.8％,respectively (P =0.074) ; the 5-year distant metastasis-free survival and overall survival between the two groups were (89.7％ vs.95.2％,P =0.001)and (96.4％ vs.98.9％,P =0.046).Multivariate analysis revealed that lymph node metastasis and adjuvant radiotherapy were independent risk factors for local-regional relapse.Distant metastasis and overall survival were determined by lymph node metastasis,adjuvant radiotherapy and age.Conclusions Age is not an independent factors affecting tumor local recurrence in Chinese young female patients of early breast cancer receiving breast conserving surgical therapy.
