Gallbladder small cell carcinoma: report of five cases and review of literature

VernacularTitle:胆囊小细胞癌五例报告
Author: Shuai HUANG ; Zhaoxu ZHENG ; Quan XU ; Xinghua YUAN
Publication Type:Journal Article
Keywords: Gallbladder neoplasms; Carcinoma hepatocellular; Cholecystectomy
From: Chinese Journal of General Surgery 2013;28(7):489-491
CountryChina
Language:Chinese
Abstract: Objective To study the clinical features of gallbladder small cell carcinoma (GSCC),to improve the diagnosis and treatment of GSCC.Methods We retrospectively analyzed the clinical data of GSCC patients at our hospital from January 2000 to January 2012,and made a collective review of the literature.Results In this series,there were four female cases,one male case,the age at the first diagnosis was between 42-67,with the median age of 57.The main complain was pain and dis-comfort on the up and right abdomen.Tumor located in the bottom of gallbladder in 3 cases,and in the body in 2.Cholelithiasis was complicated in 4 cases.2 patients received radical resection of GSCC,followed by adjuvant chemotherapy of VP-16 and cisplatin,radioactive therapy in one.Postoperatively,these two were followed up for 45 and 32 mons with tumor free survival.3 cases received palliative resection,followed by adjuvant chemoradioactive therapy or intervention treatment,these three were followed up to 8,11,30 months respectively to their death for tumor recurrence.Conclusions GSCC is a rare disease,the initial symptoms are not often specific and easily misdiagnosed.The prognosis of GSCC is poor.