Short-term Change in Corneal Endothelium after Iris-Fixed Phakic Intraocular Lens Insertion.
- Author:
Eun Suk LEE
1
;
Young Jae CHO
;
Eung Kweon KIM
Author Information
1. The Institute of Vision Research, Department of Ophthalmology, College of Medicine, Yonsei University, Seoul, Korea. eungkkim@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Corneal endothelial cell;
Iris-fixed phakic intraocular lens;
Myopia
- MeSH:
Anterior Chamber;
Endothelial Cells;
Endothelium, Corneal*;
Humans;
Microscopy;
Myopia;
Phakic Intraocular Lenses*;
Prospective Studies
- From:Journal of the Korean Ophthalmological Society
2005;46(3):410-415
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate endothelial change in phakic eyes implanted with Artisan phakic IOL inserts and to identify the associated factors. METHODS: We prospectively examined the endothelial change in 11 phakic eyes implanted with Artisan phakic IOL inserts. Noncontact specular microscopy was performed preoperatively, and at 1 week and 1 month postoperatively. RESULTS: The mean endothelial cell loss was 3.57% at 1 week, and 4.69% at 1 month. There was a statistically significant decrease in endothelial cell density and an increase in pleomorphism and polymegathism of the cells after the surgery which indicate cellular damage (p<0.05). There were no statistically significant changes in endothelial cell density, shape, or size between 1 week and 1 month postoperatively (p>0.05). No correlation was observed between cell loss and corneal curvature, critical distance, IOL optic size, IOL diopter, or serial order of the operation. However, there was significant negative correlation (R=-7.600; p>0.05) between cell loss and anterior chamber depth. CONCLUSIONS: Endothelial damage occurred primarily during the surgical procedure and special attention should be given to patients with shallow anterior chamber depth for iris-fixed phakic IOL inserts to avoid unintended endothelial damage.
