Clinical effect of exercise therapy on the patients with osteoporosis
10.3760/cma.j.issn.0254-9026.2013.08.022
- VernacularTitle:运动疗法对骨质疏松症患者的临床作用研究
- Author:
Dan SHI
;
Xiao SHI
;
Fulong LI
;
Jiangbo REN
;
Lijun GU
- Publication Type:Journal Article
- Keywords:
Osteoporosis;
Exercise therapy;
Calcifediol
- From:
Chinese Journal of Geriatrics
2013;32(8):872-874
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effect of exercise therapy on patients with osteoporosis according to osteoporosis quality of life scale(OQOLS)and the changes in biochemical markers of bone metabolism.Methods Totally 94 patients with primary osteoporosis were randomly divided into 2 groups:the intervention group [exercise therapy (Wu Xing Jian Gu Cao) with calcium/vitamin D supplementation for 90 days] and the control group (only calcium/vitamin D supplementation for 90 days].OQOLS and the changes in biochemical markers of bone metabolism were observed before and after treatment.Results Compared with before treatment,25-hydroxy vitamin D[25-(OH) D]levels were increased in control group (33 cases) and intervention group (29 cases) after treatment [(61.2± 11.1) mmol/L vs.(48.1±26.2)mmol/L,both P＜0.001],and the enhanced level was higher in the intervention group than in the control group (P＜0.05).Compared with before treatment,bone alkaline phosphatase (BALP) was decreased in control and intervention group after treatment (both P＜0.05).There were significant differences in OQOLS in both groups between before and after treatment except for the function of physical activities in intervention group (P＜0.05).Conclusions The basic and exercise therapy can both increase [25-(OH) D] level,reduce BALP,and have clinical effects on bone metabolism,while exercise therapy has an improvement in osteoporosis quality of life in patients with osteoporosis.
