Antimicrobial resistance detection of acinetobacter baumannii in Huainan of Anhui provinle

VernacularTitle:安徽省淮南地区鲍曼不动杆菌耐药性检测
Author: Xin AN ; Shaolin WANG ; Yuanhong XU
Publication Type:Journal Article
Keywords: Acinetobacter baumannii; Antimicrobial agent; Antimicrobial resistance
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(22):3364-3365
CountryChina
Language:Chinese
Abstract: Objective To investigate the antimicrobial resistance of clinical isolated acinetobacter baumannii against the common antimicrobial agents in Huainan and to direct rational medication in clinical.Methods 160 acinetobacter baumannii strains were isolated from 3 hospitals in Huainan from Oct.2010 to Jun.2012.Bacteria identification and antimicrobial susceptibility testing were detected by VITEK32 of BioMérieux company.Cefoperazone sulbactam susceptibility was detected by Kirby-Bauer method.Results The drug resistant rate of acinetobacter baumannii against 10 antimicrobial agents was beyond 50.0％ and resistant rate of aztreonam was up to 90.1％.The drug resistant rate of only 4 antimicrobial agents was lower than 50.0％.In these 4 drugs,the lowest drug resistant rate was cefoperazone sulbactam (23.4％) and antimicrobial resistant rate of imipenem and meropenem was 26.0％ and 31.2％,respectively.Conclusion The antibiotic resistance and multiple resistance of acinetobacter baumannii in Huainan is serious.Cefoperazone sulbactam and imipenem are the first drugs for clinical therapy of acinetobacter baumannii infection.