The clinical efficacy and safety of amiodarone in the treatment of elderly patients with ventricular arrhythmia

VernacularTitle:胺碘酮治疗老年室性心律失常的临床疗效及安全性
Author: Wenting AI ; Baozhou JIANG ; Lei LIANG
Publication Type:Journal Article
Keywords: Arrhythmia; Coronary disease; Amiodarone; Treatment outcome; Aged
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(20):3058-3060
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical efficacy and safety of amiodarone in the treatment of the elderly patients with ventricular arrhythmia.Methods 136 elderly patients with ventricular arrhythmia were randomly divided into the observation group (n =68cases) and control group (n =68cases).The observation group was given amiodarone by intravenous to treat the elderly ventricular arrhythmia,and patients in the control group were treated with combination therapy.After treatment for 4 weeks,the treatment outcomes were observed and compared.Results The obvious effective rate and total effective rate of the observation group was 51.47％,92.65％).which were significantly higher than those in the control group (51.47 ％,92.65 ％) (P ＜ 0.05).There was no significant difference in the incidence rate of adverse effect between the two groups (P ＞ 0.05).Conclusion Amiodarone has good clinical effect in treatment of elderly patients with ventricular arrhythmia,it is worthy of clinical use.