Contrast of therapeutic effects between voriconazole and fluconazole in treatment of pulmonary candidiasis

VernacularTitle:氟康唑与伏立康唑治疗念珠菌肺炎的疗效比较
Author: Xianbin ZHAO ; Junkui ZHAO ; Xiaoke ZHANG
Publication Type:Journal Article
Keywords: Lung diseases,fungal; Voriconazole; Fluconazole
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(19):2931-2932
CountryChina
Language:Chinese
Abstract: Objective To observe the efficacy and safety of voriconazole in the treatment for the patients infectedwith Candida species.Methods 79 patients were randomly divided into voriconazole treatment group and fluconasole treatment group.And they were enrolled and were administered voriconazole.Results The total effective rate of experimental group was 93.1％,and that of control group was 65.9％ and the difference was significant(P ＜0.05).the risk factors of the two groups showed no obvious difference.the adverse reaction incidence rate in voriconazole treatment group was 16.7％,And that in fluconazole treatment group was 14.0％,there was no significant difference between the two groups.Conclusion The application of voriconazole can receive better effect than that of fluconasole.And it has good clinical safety,and voriconazole is worthy of application in clinic for Candida infection.