Clinical observation of 125I seed treatment of recurrence of glioma and the environmental radiation

VernacularTitle:125I粒子治疗复发脑胶质瘤疗效及对环境辐射观察
Author: Lihai SHI ; Nan ZHANG ; Feng ZUO
Publication Type:Journal Article
Keywords: Iodine radioisotopes; Glioma
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(19):2900-2902
CountryChina
Language:Chinese
Abstract: Objective To observe 125I seed treatment effect and environmental radiation in the treatment of recurrent glioma.Methods 64 patients with recurrent glioma patients,according to the wishes of patients and their families were divided into observation group of 30 cases and a control group of 34 patients.Clinical outcomes and follow-up of 125I seeds around radiation were compared between the two groups.Results The treatment efficiency of observation group and control group was 60.0％ (18/30),and 35.3％ (12/34),respectively,which was statistically significant(x2 =8.39,P ＜0.05).Follow-up from 0 to 6 months,the ambient radiation rapidly decreased as the distance increaseing with the implantation point,radiation dose in a distance of 40cm has been close to the natural basis of radiation dose;125I seeds measured radiation dose continued to decay with increasing time after implantation.Four months later,it was close to the natural basis of radiation dose.Conclusion Conclusion 125I radioactive particles in the treatment of recurrent glioma have good curative effect.The effects of radiation on the surrounding environment crowd are easily protected.