Observation of the effect of Deanxit in the treatment of elderly patients with anxiety and depression after PCI

VernacularTitle:氟哌噻吨-美利曲辛对老年人冠脉介入术后焦虑抑郁的疗效观察
Author: Guoliang YANG ; Shaohui ZHANG ; Lixin LIU ; Guanghe WEI ; Jianjun WANG
Publication Type:Journal Article
Keywords: Anxiety; Depression; Flupentixol; Melitracen; Angioplasty,transluminal,percutaneous coronary
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(20):3107-3108
CountryChina
Language:Chinese
Abstract: Objective To investigate the effects of Deanxit on elderly patients with anxiety and depression symptoms after percutaneous coronary intervention (PCI).Methods The Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale(HAMD) were used to evaluate the anxiety and depression symptoms in elderly patients (more than 70 years old) with coronary heart disease after PCI.Thus,80 patients with anxiety and depression after PCI were singled out,they were randomly divided into Deanxit group (n =40,2 Deanxit tablets daily) and control group (n =40,conventional therapy).HAMA and HAMD scores were performed after treatment for 12 weeks.Results HAMA and HAMD scores of the Deanxit group were (10.2 ± 5.7) points,(11.8 ± 6.2) points,which were significantly lower than (17.8 ±5.5)points,(18.3 ±4.3)points in the control group (P =0.012,P =0.020).Conclusion Deanxit can significantly improve the anxiety and depression symptoms in elderly patients after PCI.