Study on the correlation between plasm homocysteine with carotid intima-media thickness in patients with type 2 diabetes

VernacularTitle:2型糖尿病患者血浆同型半胱氨酸与颈动脉内膜中层厚度的相关性研究
Author: Xiang LUO
Publication Type:Journal Article
Keywords: Homocysteine; Atherosclerosis t Diabetes
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(18):2800-2801
CountryChina
Language:Chinese
Abstract: Objective To investigate the correlation between the plasm level of homocysteine(Hcy) and carotid intimal-medial thickness(IMT) in type 2 diabetes(T2DM).Methods 54 patients with preliminary diagnosis of T2DM were divided into two groups according to IMT level:normal IMT group and IMT increased group.30 healthy people were chosen as control.Hcy were detected in all patients and healthy people.Results Hcy levels in T2DM was (24.77 ± 10.17) μmol/L,which was higher than that in healthy people [(10.95 ± 2.60) μmol/L] (P ＜ 0.05).Hcy levels in IMT increased group was (19.80 ±4.97)μmol/L,which was higher than that in normal IMT group [(15.00 ±4.83) μmol/L] (P ＜ 0.05).The positive correlation between Hcy and IMT in T2DM was shown (r =0.6384,P ＜ 0.05).Conclusion High Hcy was an independent risk factor of atherosclerosis in patients with type 2 diabetes.