Influence of immune and nutrition therapy on the rehabilitation of patients with severe traumatic brain injury
10.3760/cma.j.issn.1008-6706.2013.18.027
- VernacularTitle:免疫营养对重型颅脑损伤患者康复的影响
- Author:
Liping ZHAI
;
Jun SU
- Publication Type:Journal Article
- Keywords:
Craniocerebral trauma;
Immunity,nutrition therapy;
Prognosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(18):2786-2788
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of immune and nutrition therapy on the rehabilitation of patients with severe traumatic brain injury.Methods According to the different nutritional therapy,80 patients with severe traumatic brain injury were divided into the control group and observation group,each group 40 cases.The patients of the two groups were all given similarly conventional methods,and the observation group were given immune nutrition therapy,the control group were given routine nutrition therapy.After 14d,30d treattnent,nutritional status of the two groups were observed.Barthel Index,Fugl-Meyer score of the two groups of patients and recovery of neurological function were compared 3 months after treatment.Results After treatment,ALB and TF increased significantly (t =5.75,6.38,1.27,2.63,all P < 0.05) ;ALB and TF in the observation group 14 d and 30 d after treatment were significantly higher than those of the control group (t =11.26,6.53,1.27,1.68,all P < 0.05).After 3 months of treatment between the two groups,the clinical efficacy of the observation group was 60.00%,which was better than that of control group(37.50%) (χ2 =9.67,P < 0.05),the differences of Barthel Index and,Fugl-Meyer score were statistically significant (t =3.24,2.88,all P < 0.05).Conclusion The immune and nutritional therapy can significantly promote the neurological function recovery of patients with severe traumatic brain injury,so as to improve the prognosis and the patients's quality of life.