Clinical value of combined examination of CT and serum tumor marker in evaluation of prognosis of peripheral lung cancer

VernacularTitle:血清肿瘤标记物联合CT检查在周围型肺癌预后评价中的价值
Author: Zhengyu HU
Publication Type:Journal Article
Keywords: Tomography,X-ray computed; Tumor markers,biological; Lung neoplasms
From: Chinese Journal of Primary Medicine and Pharmacy 2013;20(17):2624-2626
CountryChina
Language:Chinese
Abstract: Objective To explore the value of combined examination of CT and tumor marker in evaluation of prognosis of peripheral lung cancer.Methods 204 patients diagnosed as peripheral lung cancer were selected in this research and they were followed up for 3 years.CT plain and contrast-enhanced scan was applied to calculate the density of tumor edge enhancement.Serum levels of tumor markers including CEA,CA125,CY211 and CA 199 were examined in peripheral blood.The prognostic value of CT and/or tumor markers in evaluation of metastasis after 1,2 and 3 years was assessed.Results Serum level of CY211 was significantly correlated with metastasis rate after 1,2 and 3 years after diagnosis of peripheral lung cancer(r =0.763,P ＜0.05) ;metastasis rate increased significantly after 1,2 and 3 years along with increase of density of tumor edge enhancement.Combined examination of CT and CY211 increased detectable rate of metastasis of peripheral lung cancer.Conclusion Combined examination of CT and CY211 can increase detectable rate of metastasis,benefit evaluation of prognosis of peripheral lung cancer.