Effection of lung fluid clearance disturbance in late preterm infants with respiratory distress syndrome
10.3760/cma.j.issn.1673-4408.2013.03.001
- VernacularTitle:肺液吸收障碍在晚期早产儿呼吸窘迫综合征中的作用
- Author:
Li WANG
- Publication Type:Journal Article
- Keywords:
Late preterm infants;
Respiratory distress syndrome;
Lung fluid clearance disturbance;
α-ENaC
- From:
International Journal of Pediatrics
2013;(3):217-219
- CountryChina
- Language:Chinese
-
Abstract:
In recent studies,it has been demonstrated that the clinical efficacy of surfactant is poor for late protein infants.Besides,this kind of infants have not infection or other risk factors that may lead to respiratory distress syndrome(RDS).Thus,it is speculated that the pathogenesis of RDS of late preterm infants is different from preterm infants.New researches show that,as the key point of Lung fluid transport via Epithelium,α-ENaC plays an important role in the pathogenesis of RDS of late preterm infants through the inhibition of lung fluid clearance and activity of surfactant.This review highlights the most important mechanisms of Lung fluid absorption barrier in RDS of late preterm infants.
