Clinical research on the relationship between breast cancer and thyroid disorder

VernacularTitle:乳腺癌与甲状腺疾病相关性的临床研究
Author: Yanjie ZHAO ; Ruibin WANG ; Yuguang SONG ; Jun REN
Publication Type:Journal Article
Keywords: Breast neoplasms; Thyroid diseases
From: Cancer Research and Clinic 2013;(3):178-180
CountryChina
Language:Chinese
Abstract: Objective To investigate the incidence of autoimmune and nonautoimmune thyroid diseases in patients with breast cancer.Methods Clinical and ultrasound evaluation of thyroid gland,detection of serum thyroid hormone and related antibodies,and fine-needle aspiration of thyroid gland were performed in 100 breast cancer patients and 100 control individuals during the period from 2004 to 2008.Results The mean values of anti-thyroid peroxidase antibodies were significantly higher in breast cancer patients than that in control individuals [(104.56±21.54) U/ml vs (22.16±4.65) U/ml,(P=0.030)].The incidence rates of autoimmune and nonautoimmune thyroid diseases were higher in breast cancer patients than that in control individuals[38 ％ (38/100) vs 17 ％ (17/100),P=0.0009,26 ％ (26/100) vs 9 ％ (9/100),P =0.0016,respectively].Conclusion The results indicate an increased incidence of autoimmune and nonautoimmune thyroid diseases in breast cancer patients.