Diagnostic value of a new tumor marker CK19-2G2 for lung cancer

VernacularTitle:新型肿瘤标志物细胞角蛋白19片段2G2诊断肺癌的临床价值
Author: Hongyan ZHANG ; Feng LIANG ; Chang LIU ; Zhiling JIA
Publication Type:Journal Article
Keywords: Lung neoplasms; Karatin-19; CYFRA21-1
From: Cancer Research and Clinic 2013;(3):145-147
CountryChina
Language:Chinese
Abstract: Objective To investigate the diagnostic value of a new tumor marker CK19-2G2 for lung cancer.Methods The serum levels of CK19-2G2 in 150 lung cancer patients,50 pulmonitis patients and 50 healthy controls were detected with chemoluminescence.The diagnostic efficacy between the serum levels of CK19-2G2 and CYFRA21-1 were compared.Results The sensitivity and accuracy of CK19-2G2 were 55.3 ％ (83/150) and 80.3 ％ (281/350),respectively,while the sensitivity and accuracy of CYFRA21-1 were 28.0 ％ (42/150) and 67.4 ％ (236/350),respectively.The differences were significant (P ＜ 0.001).Conclusion The detection of CK19-2G2 may be a new diagnostic tumor marker for lung cancer.