Incidence of depression in patients with advanced malignancy and its effect on quality of life

VernacularTitle:晚期恶性肿瘤患者抑郁状态对生活质量的影响
Author: Mei YE ; Zhengzhi FENG ; Keyu LIU ; Huoming CHEN
Publication Type:Journal Article
Keywords: Advanced malignancy; Depression; Quality of life
From: Cancer Research and Clinic 2013;(4):260-262
CountryChina
Language:Chinese
Abstract: Objective To investigate the incidence of depression in patients with advanced malignancy and its effect on quality of life.Methods Patients with advanced malignancy were evaluated with Beck depression and quality of life questionnaires.The correlation of Beck depression scoring with quality of life was analyzed.Results A total of 230 in-patients with advanced malignancy were enrolled in this study and 213 copies of valid questionnaire were collected.95.3 ％ (203/213) patients had depression.The Beck depression scoring had positive correlation with body,role,mood,cognition,society,vomiting,pain,dyspnea,agrypnia and appetite (all P ＜ 0.05),and had negative correlation with total health factors (r =-0.296,P ＜ 0.01).Conclusion Depression is prevalent in patients with advanced malignancy and correlated with quality of life.Therefore,psychological interventions are needed to relief depression and improve quality of life.