Determination and clinical significance of serum hypersensitivity C-reactive protein and hypersensitivity cardiac troponin in patients with coronary heart disease
10.3760/cma.j.issn.1008-6706.2013.12.023
- VernacularTitle:冠心病患者血清超敏C-反应蛋白、超敏肌钙蛋白T检测及意义
- Author:
Rensen DAI
;
Weilin LI
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Ventricular function,left;
C-reactive protein;
Troponin T
- From:
Chinese Journal of Primary Medicine and Pharmacy
2013;20(12):1814-1816
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the determination of hypersensitivity C-reactive protein(Hs-CRP) and cardiac troponin T(Hs-cTnT) in patients with coronary heart disease,and to analyze the correlation with cardiac function.Methods The function of left ventricle and the serum levels of Hs-CRP and Hs-cTnT in 100 patients with coronary heart disease and 50 healthy subjects were detected.Results The function of left ventricle and the serum levels of Hs-CRP and Hs-cTnT were significantly different in patients with coronary heart disease and healthy subjects(P ＜0.01).The function of left ventricle and the serum levels of Hs-CRP and Hs-cTnT were significantly different in coronary heart disease patients with different New York Heart Association class(P ＜ 0.01).The serum levels of Hs-CRP and Hs-cTnT were positively correlated with class of New York Heart Association,left ventricular end diastolic diameter,and negatively correlated with left ventricular ejection fraction and fraction shortening (Absolute value of r:0.536 ～ 0.849,P ＜ 0.05).Conclusion The serum levels of Hs-CRP and Hs-cTnT significantly increase in patients with coronary heart disease,which is correlated to function of left ventricle,and it can be used as the indicators of cardiac function in patients with coronary heart disease.
