Efficacy analyses of capsules Shugan-jieyu and paroxetine in patients with poststroke depression and anxiety

VernacularTitle:舒肝解郁胶囊联合帕罗西汀治疗脑卒中后抑郁焦虑的疗效观察
Author: Yunhua YUE ; Xiaoning ZHANG ; Liping ZHANG ; Xiaoying YANG ; Jieping MAO ; Reyi MIHE
Publication Type:Journal Article
Keywords: Poststroke depression and anxiety; Shugan-jieyu
From: Chinese Journal of General Practitioners 2013;(6):483-485
CountryChina
Language:Chinese
Abstract: A total of 192 poststroke patients with depression and anxiety were assigned randomly into study group (n =96) and control group (n =96).The study group received both capsules Shugan-jieyu and paroxetine while the control group paroxetine alone.Compared with the control group,scores of both Hamilton depression scale (HAMD) and Hamilton anxiety scale (HAMA) were significantly different at the end of week 2 and 6 in the study group (P ＜ 0.05).The HAMD and HAMA deduction rate and the scores of mangled extremity severity,mini-mental state examination and modified Barthel index at the end of week 6 of the study group were better than those of the control group (all P ＜ 0.05).The combined use of capsules Shugan-jieyu and paroxetine could improve symptoms of depression and anxiety,offer a higher safety and accelerate the rehabilitation of extremity function.