Association between chronotropic incompetence and metabolic equivalents in type 2 diabetic mellitus patients complicated with metabolic syndrome

VernacularTitle:2型糖尿病合并代谢综合征患者心脏变时功能与代谢当量的观察
Author: Min GAO ; Wei CHEN ; Zunke GONG ; Liang HAN ; Li ZHANG
Publication Type:Journal Article
Keywords: Type 2 diabetes mellitus; Metabolic syndrome; Electrocardiographic exercise testing; Chronotropic incompetence; Metabolic equivalents
From: Chinese Journal of General Practitioners 2013;(6):431-434
CountryChina
Language:Chinese
Abstract: Objective To investigate the association between chronotropic incompetence (CI)and motor ability in type 2 diabetic mellitus (T2DM) patients complicated with metabolic syndrome (MS).Methods One hundred and twenty patients with T2DM were enrolled in the study,including 66 cases with MS (MS group) and 54 without MS (non-MS group).The electrocardiographic exercise test was performed,the CI indexes including ratio of heart rate (rHR),heart rate reserve (HRR)were measured and the max metabolic equivalents(maxMETs) were calculated.Result The rHR(0.77 ±0.04 vs.0.81 ±0.06,t =3.41,P ＜ 0.05),HRR (0.62 ± 0.05 vs.0.70 ± 0.07,t =5.96,P ＜ 0.05) and maxMETs (8.8 ± 1.1 vs.9.7 ± 1.2,t =0.16,P ＜ 0.05) in patients of MS group all lower than those in non-MS group.The maxMETs were positively correlated with rHR (r =0.81,P ＜ 0.05) and HRR (r =0.78,P ＜ 0.05).Conclusion The results indicate that CI as well as maxMETs and rating of perceived exertion can be used as monitoring index in type 2 diabetic patients complicated with metabolic syndrome.