Analysis of risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly undergoing health examination
10.3760/cma.j.issn.0254-9026.2013.05.010
- VernacularTitle:老年体检人群良性前列腺增生合并代谢综合征危险因素分析
- Author:
Leilei WANG
;
Jianlong WANG
;
Ling ZHU
- Publication Type:Journal Article
- Keywords:
Prostatic hyperplasia;
Metabolic syndrome X;
Risk factors
- From:
Chinese Journal of Geriatrics
2013;(5):496-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalences of benign prostatic hyperplasia (BPH) and metabolic syndrome (MS) and to analyze the risk factors for benign prostatic hyperplasia and metabolic syndrome in the elderly.Methods A total of 490 elderly men undergoing health examination in our hospital from January 2010 to December 2010 were divided into BPH and MS group (n=246),MS group (n=55),BPH group (n=44),non-BPHandnon-MSgroup (control,n =145).Body height,body weight,body mass index (BMI),systolic blood pressure (SBP),diastolic blood pressure (DBP) were detected.Fasting blood glucose (FBG),serum total cholesterol (TC),triglyceride (TG),low-density lipoprotein cholesterol (LDL-C),high-density lipoprotein cholesterol (HDL-C),alanine a minotransferase (ALT),creatinine (CRE),glycated hemoglobin (HbA1c),serum uric acid (UA) and other indicators were measured.Results The prevalences of BPH and MS were increased with age (x 2=810.71,732.18,both P<0.05).Age,BMI,blood pressure,the levels of FBG,TG,TC,LDL-C,UA and HbA1c were significantly higher in BPH and MS group than in control group (all P<0.05),while HDL-C concentration was significantly lower in group BPH and MS than in control group (P<0.05).Age was significantly higher in group BPH and MS than in MS group (P<0.05).Age,BMI,blood pressure,levels of FBG and TG were significantly higher in group BPH and MS than in BPH group (all P<0.05),while HDL-C concentration was significantly lower in group BPH and MS than in group C (P<0.05).Multivariate logistic regression analysis showed that age>70 years,obesity,hypertension,high FBG,high TG,lower HDL-C were independent risk factors for BPH and MS (OR:2.947,4.470,4.790,11.589,27.850,0.391,respectively,all P< 0.05).Conclusions The prevalences of BPH and MS are gradually increased with ageing in elderly men.Age > 70 years,obesity,hypertension,high fasting glucose,hypertriglyceridemia and lower HDL-C are the risk factors for BPH and MS.