The variables in normalizing glomerular filtration rate
10.3760/cma.j.issn.2095-2848.2013.03.023
- VernacularTitle:肾小球滤过率的标准化参数
- Author:
Fei LI
;
Hongwei SI
;
Jianhua GENG
;
Shengzu CHEN
- Publication Type:Journal Article
- Keywords:
Glomerular filtration rate;
Radionuclide imaging;
Body surface area;
Body fluids;
Body weight
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2013;(3):238-240
- CountryChina
- Language:Chinese
-
Abstract:
Normalizing GFR with variables is important for non-cancer patients,especially for kidney donors.The most frequently evaluated variables are body surface area (BSA),extracellular fluid volume (ECV) and lean body mass (LBM).It is difficult to accurately quantify BSA and the power of BSA normalization decreases in children and obesity population.The ECV normalization is suitable for healthy children,but its clinical value decreases in patients with damaged renal function.The LBM can be accurately measured and has a larger serviceable range in the normalization.Although the influence factors of LBM should be extensively evaluated,the available data indicate that LBM is more suitable in the normalization of GFR than BSA and ECV.
