Clinical significance of platelet count,fibrinogen and D-dimer detection in patients with cervical cancer
10.3760/cma.j.issn.1673-4904.2013.15.004
- VernacularTitle:宫颈癌患者血小板计数、纤维蛋白原、D-二聚体检测的临床意义
- Author:
Lin LI
;
Peiling LI
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
Platelet count;
Fibrinogen
- From:
Chinese Journal of Postgraduates of Medicine
2013;(15):12-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical value of the platelet count (PC),fibrinogen (Fib) and D-dimer detection in patients with cervical cancer.Methods Eighty-seven patients with cervical cancer (cervical cancer group) and 66 patients with cervical benign lesion (control group) were selected,the levels of PC,Fib and D-dimer were respectively determined to analyze the clinical significance of three factors.Results The PC,Fib and D-dimer in cervical cancer group were significantly higher than those in control group [(274.22 ± 82.32) × 109/L vs.(238.82 ±74.97) × 109/L,(3.03 ±0.59) g/L vs.(2.67 ±0.45) g/L,(182.77 ± 167.07) ng/L vs.(113.74 ± 64.84) ng/L,P ＜ 0.05].Patients with stage Ⅱ and tumor volume ＞ 4 cm were obviously higher than patients with stage Ⅰ and tumor volume ≤ 4 cm in the PC,Fib and D-dimer [(296.66 ±94.30) × 109/L vs.(251.26 ±60.86) × 109/L,(3.22 ±0.67) g/L vs.(2.84 ±0.42) g/L,(238.61 ± 213.29) ng/L vs.(125.63 ± 62.96) ng/L,(299.14 ± 81.33) × 109/L vs.(257.44 ± 79.39) ×109/L,(3.20±0.67) g/Lvs.(2.91 ±0.50) g/L,(281.29 ±223.33) ng/L vs.(116.46 ±51.69) ng/L,P＜0.05].But there was no significant difference between lymph node metastasis positive patients and lymph node metastasis negative patients (P ＞ 0.05).Conclusion The PC,Fib and D-dimer of patients with cervical cancer are helpful to clinical cervical cancer diagnosis,treatment and prognosis improvement.
