A study on correlation between global end-diastolic volume index and central venous pressure in fluid resuscitation in patients with severe sepsis
10.3969/j.issn.1008-9691.2013.04.022
- VernacularTitle:严重脓毒症液体复苏中全心舒张期末容积指数与中心静脉压的相关性研究
- Author:
Zhuheng WANG
;
Jing ZHANG
;
Yuwei LI
;
Jin WANG
;
Hongxia CHANG
- Publication Type:Journal Article
- Keywords:
Central venous pressure;
Global end diastolic volume index;
Severe sepsis
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2013;(4):248-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between global end diastolic volume index(GEDI)and central venous pressure(CVP)of severe sepsis patients during fluid resuscitation by pulse induced continuous cardiac output(PiCCO )test. Methods Sixty-four severe sepsis patients had been treated by fluid resuscitation strictly in accordance with the guidelines for treatment of sepsis in 2008. During the treatment,GEDI and corresponding CVP data were measured and recorded to observe the correctness of volume reaction under different CVP ranges,and the relativity between GEDI and CVP was analyzed. Results In the whole process of monitoring circulatory blood volume,no significant correlation between CVP and GEDI(r=-0.012,P>0.05)was found in severe patients with severe sepsis. When the CVP was in 0-8 mm Hg(1 mm Hg=0.133 kPa)or greater than 12 mm Hg,there was no correlation with the GEDI(r=-0.009,-0.020,respectively,both P>0.05). When the CVP was in 8-12 mm Hg at the 6 hours resuscitation target required by the guidelines,there was an obvious positive correlation between CVP and GEDI(r=0.653,P<0.01). Conclusion CVP is not suitable to be an exclusive target indicator for fluid resuscitation volume.
