Risk factors of iatrogenic pancreatitis following endoscopic retrograde cholangiopancreatography : a meta-analysis

VernacularTitle:经内镜逆行胰胆管造影操作因素对术后胰腺炎发生的影响
Author: Jianjun CHEN ; Ximo WANG ; Wen LI
Publication Type:Journal Article
Keywords: Cholangiopancreatography,endoscopic retrograde; Pancreatitis; Risk factors; Meta-analysis
From: Chinese Journal of Hepatobiliary Surgery 2013;(6):405-410
CountryChina
Language:Chinese
Abstract: Objective To study the iatrogenic risk factors of post-ERCP pancreatitis (PEP).Method A meta-analysis was carried out on 15 clinical studies which included more than 100 patients published in the medical literature in the last twenty years.Result When the risk factors were analysed,OR for endoscopic sphincterotomy (EST) was 3.75 (95％CI 3.01-4.68),OR for papillae precut was 2.17 (95％CI 1.76-2.67),OR for biliary sphincter balloon dilation was 1.66 (95％CI 1.16-2.39),OR for pancreatic contrast injection was 2.79 (2.31-3.37),OR for sphincter of Oddi manome try was 5.86 (95％CI 5.04-6.80),OR for pancreatic stenting was 2.57 (95％CI 2.09-3.17).Conclusion The analysis indicated EST,papillae precut,balloon dilation,pancreatic contrast injection,Oddi manometry,non-prophylactic pancreatic duct stenting were the risk factors of post-ERCP pancreatitis.