Application of endoscopy combined with 125I seed implantation in the pancreatic cancer surgery in elderly patients
10.3760/cma.j.issn.0254-9026.2013.04.011
- VernacularTitle:内镜联合125I粒子植入在老年胰腺癌患者手术治疗中的应用
- Author:
Yian DU
;
Yanping YU
;
Shi WANG
;
Xiangdong CHENG
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Endoscopes,gastrointestinal;
Iodine radioisotopes;
Palliative care
- From:
Chinese Journal of Geriatrics
2013;(4):390-392
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the application of endoscopy combined with 125I seed implantation in the pancreatic cancer palliative surgery in elderly patients.Methods A total of 78 elderly patients with pancreatic cancer who can not be treated with radical operation were divided into observation group and control group (n=39 each group).All patients were treated with stent intervention.Patients in the ation group were treated with 125I seed implantation guided by CT or ultrasonangraphy additionally.The clinical symptoms were compared between groups.The survival time and complications of the patients were recorded during the follow-up.Results The clinical symptoms of patients in both two groups were greatly improved (x2 =0.06,P＞0.05).Compared with the control group,the pain remission was better and the incidence of pain caused by pancreatic cancer was lower in the observation group (46.2％ vs.76.9％,x2 =7.80,P＜0.05).There was a significant difference in the average of survival time between the observation group and control group [(13.7±3.4) months vs.(8.4±3.8) months,t=3.73,P＜0.01],but no statistical difference was found in the long-term survival rate between groups.There was no significant difference in the incidence of complications between the two groups (10.3％ vs.7.7％,x2=0.15,P＞0.05).Conclusions Endoscopy combined with 125Ⅰ seed implantation is an effective treatment for elderly patients with advanced pancreatic cancer,which can effectively relieve the clinical symptoms,proiong the survival time,reduce the pain and complications.
