Clinical efficacy of combined treatment with montelukast and intranasal steroid for chronic adenoid hypertrophy in children

VernacularTitle:孟鲁司特联合鼻内激素治疗儿童腺样体肥大的临床观察
Author: Chao CHEN ; Dabo LIU ; Shaofeng LIU ; Shuyao QIU
Publication Type:Journal Article
Keywords: adenoid; montelukast; treatment; child
From: Journal of Clinical Pediatrics 2013;(7):629-631
CountryChina
Language:Chinese
Abstract: Objectives To observe the clinical efficacy of combined treatment with montelukast and intranasal steroid for chronic adenoid hypertrophy in children. Methods 47 children with chronic adenoid hypertrophy were selected and ran-domly divided into drug combination group (n=23) treated with montelukast combined with intranasal steroids for two months and control group (n=24) treated with intranasal steroids only for two months. Clinical efficacy was compared between two groups by clinical score and the result of fibronasopharyngoscopy. Results The clinical scores were 0 (0, 1.0) and 0(0, 0) at 2 weeks and 2 months after treatment in combination group, and 1.0 (1.0, 1.0) and 0 (0, 1.0) in control group. There were sig-nificant differences between two groups (Z=2.404, P<0.05;Z=2.069, P<0.05). Conclusions The clinical efficacy of combined treatment with Montelukast and intranasal steroid is better than that of treatment with intranasal steroid only in children with chronic adenoid hypertrophy.