Research advance of brain natriuretic peptide in the diagnosis and treatment of pediatric cardiovascular disease
10.3969/j.issn.1000-3606.2013.07.021
- VernacularTitle:脑钠肽在儿童心血管疾病诊治中的研究进展
- Author:
Liwei WU
;
Fengming WANG
- Publication Type:Journal Article
- Keywords:
brain natriuretic peptide;
N-terminal brain natriuretic peptide;
cardiovascular disease;
child
- From:
Journal of Clinical Pediatrics
2013;(7):679-682
- CountryChina
- Language:Chinese
-
Abstract:
Brain natriuretic peptide(BNP) is a cardiac hormone mainly secreted by myocytes in the ventricular wall. It has strong action of natriuresis, diuresis, vasodilation, inhibition of renin-angiotensin-aldosterone system and sympathetic nervous system. The increased levels of BNP and NT-proBNP have been reported in children’s cardiovascular diseases in numerous stu-dies and can reflect cardiac function. This article simply reviews the BNP and NT-proBNP about its biology character, detection method, medical reference range and its progress in pediatric cardiovascular disease.
