Curative effect comparison on different dose of glucocorticoid in treatment of acute low-frequency descent type sensorineural deafness
10.3760/cma.j.issn.1673-4904.2013.15.010
- VernacularTitle:不同剂量糖皮质激素在急性低频下降型感音神经性聋治疗中的疗效比较
- Author:
Haixia LI
- Publication Type:Journal Article
- Keywords:
Deafness;
Glucocorticoids;
Hearing loss,sensorineural
- From:
Chinese Journal of Postgraduates of Medicine
2013;(15):28-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study curative effect on different dose of glucocorticoid in treatment of acute low-frequency descent type sensorineural deafness.Methods Sixty patients with acute low-frequency descent type sensorineural deafness were divided into high dose group,low dose group and control group according to the dose of glucocorticoid with 20 cases each,all the patients were given corresponding suit support treatment,on the basis of high dose group patients were given every day once intravenous drip methylprednisolone 80 mg for 5 d,low dose group patients were given every day once intravenous drip methylprednisolone 60 mg for 5 d,control group patients did not give glucocorticoid.The curative effect of 3 groups was observed.Results The total effective cases of high dose group was significantly more than that of low dose group and control group (18 cases vs.14 cases and 7 cases),and low dose group was significantly more than control group,there were significant differences (P ＜ 0.05).The high dose group and low dose group were no obvious adverse reactions associated with the use of glucocorticoid.Conclusion The patients with acute low-frequency descent type sensorineural deafness treated with high dose glucocorticoid therapy has better curative effect,can significantly improve patients with clinical symptoms,it is worthy of clinical application.
