Sedative effect analysis of dexmedetomidine administered at different infusing rates in senile cataract patients with retrobulbar nerve block
10.3760/cma.j.issn.1673-4904.2013.15.006
- VernacularTitle:老年白内障手术球后神经阻滞中右美托咪定不同速率的镇静效果分析
- Author:
Dapeng YANG
- Publication Type:Journal Article
- Keywords:
Dexmedetomidine;
Cataract;
Nerve block
- From:
Chinese Journal of Postgraduates of Medicine
2013;(15):18-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the sedative effect of dexmedetomidine administered at different infusing rates in senile cataract patients with retrobulbar nerve block.Methods Eighty-four senile cataract patients with retrobulbar nerve block were divided into Ⅰ,Ⅱ and Ⅲ group by random systematic sampling method with 28 cases each,the dexmedetomidine infusing rates were 0.2,0.4 and 0.6 μg/(kg·h) accordingly.Ramsay score and mean arterial pressure (MAP),heart rate (HR),respiratory rate (RR),pulse oxygen saturation (SpO2) were recorded before anesthesia (T0),after retrobulbar nerve block (T1),and 1 0,20,30,60min after sedative administration (T2-T5).Results Ramsay scores were higher in three groups at T2-T5 than that at T0 [Ⅰ group:(2.6 ± 0.7),(2.5 ± 0.2),(2.4 ± 0.8),(2.4 ± 0.3) scores vs.(2.0 ± 0.0) scores,Ⅱ group:(3.0 ± 0.7),(3.8 ± 0.7),(4.2 ± 0.2),(4.5 ± 0.2) scores vs.(2.0 ± 0.0) scores,Ⅲ group:(3.8 ±0.6),(4.7 ± 0.4),(5.2 ± 0.8),(5.6 ± 0.6) scores vs.(2.0 ± 0.0) scores],Ⅲ group was higher than Ⅰ group and Ⅱ group,Ⅱ group was higher than Ⅰ groupatT3-T5,difference was statistically significant (P＜0.05).HR was slower in three groups at T3-T5 than that at T0 (P ＜ 0.05),Ⅲ group was slower than Ⅰgroup and Ⅱ group,difference was statistically significant (P＜0.05).There were no significant changes in MAP,RR and SpO2 among groups and the group (P ＞ 0.05).Conclusion Bolus infusion dexmedetomidine 0.5 μ g/kg followed by intravenous infusion at 0.2-0.4 μ g/ (kg· h) is suitable for sedation of senile patients with cataract surgery.
